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  anal cancer is an uncommon malignancy that starts in the anus-- the opening at the end of the rectum. Anal cancer is a cancer which arises from the anus, the distal opening of the gastrointestinal tract. Symptoms may include bleeding from the anus or a lump near the anus. Other symptoms may include pain, itchiness, or discharge from the anus. At first, most people assume the bleeding is caused by hemorrhoids (painful, swollen veins in the anus and rectum that may bleed). They are a benign and fairly common cause of rectal bleeding. Anal cancer is a malignant (cancerous) tumor of either the anal canal or anal verge. In the united states, 80 of anal cancers are squamous cell cancers, resembling the cells found in the anal canal. In japan, 80 of anal cancers are adenocarcinomas, resembling the glandular cells seen in. With anal cancer, malignant cells grow in the tissues of the anus. Infection with the human papillomavirus (hpv) increases your risk. A lump near the anus, anal discharge, bleeding, itching, and pressure are signs and symptoms. In a biopsy (by-op-see), the doctor takes out a small piece of tissue where the cancer seems to be. A biopsy is the only way to know for sure if you have cancer. For anal cancer, a biopsy is most often done during an endoscopy. Anal warts are growths that can develop on the skin around the anus (called perianal skin) and on the lining of the anal canal. If they arent treated, anal warts may increase the risk of developing anal intraepithelial neoplasia (ain) and anal cancer. Invasive anal cancer is curable in a great number of patients, particularly when it is diagnosed early and tumors are small. Anal cancers are most commonly treated with a combination of chemotherapy and radiation, which is discussed in further detail in the treatment section but can be expected to cause the tumors to completely regress in 80 to.

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